Highly selective tridentate fluorescent probes for visualizing intracellular Mg2+ dynamics without interference from Ca2+ fluctuation was written by Matsui, Yusuke;Sadhu, Kalyan K.;Mizukami, Shin;Kikuchi, Kazuya. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2017.Synthetic Route of C6H5ClO2 The following contents are mentioned in the article:
We developed highly selective fluorescent Mg2+ probes based on a novel tridentate Mg2+-selective chelator. The superior selectivity for Mg2+ over Ca2+ enabled the detection of intracellular Mg2+ concentration changes without any response to Ca2+ influx. The new probes are potential keys to elucidating intracellular Mg2+ dynamics under conditions of extremely sharp Ca2+ fluctuation. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Synthetic Route of C6H5ClO2).
4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Synthetic Route of C6H5ClO2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics