Dual Catalytic Platform for Enabling sp3 α C-H Arylation and Alkylation of Benzamides was written by Rand, Alexander W.;Yin, Hongfei;Xu, Liang;Giacoboni, Jessica;Martin-Montero, Raul;Romano, Ciro;Montgomery, John;Martin, Ruben. And the article was included in ACS Catalysis in 2020.Safety of 1-Bromo-6-chlorohexane The following contents are mentioned in the article:
A dual catalytic sp3 α C-H arylation and alkylation of benzamides with organic halides is described. This protocol exhibits an exquisite site selectivity, chemoselectivity, and enantioselectivity pattern, offering a complementary reactivity mode to existing sp3 arylation or alkylations via transition metal catalysis or photoredox events. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3Safety of 1-Bromo-6-chlorohexane).
1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Safety of 1-Bromo-6-chlorohexane
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics