Synthesis of 2-(pyrrolidin-1-yl)pyrimidines by reactions of N-(4,4-diethoxybutyl)pyrimidin-2-amine with (hetero)aromatic C-nucleophiles was written by Smolobochkin, Andrey V.;Rizbayeva, Tanzilya S.;Gazizov, Almir S.;Voronina, Julia K.;Chugunova, Elena A.;Akylbekov, Nurgali I.;Appazov, Nurbol O.;Burilov, Alexander R.;Pudovik, Michael A.. And the article was included in Chemistry of Heterocyclic Compounds in 2019.Application of 95-88-5 The following contents are mentioned in the article:
A method was developed for the synthesis of 2-(pyrrolidin-1-yl)pyrimidines I•CF3CO2H [R = 2,4-di-OH-5-ClC6H2, 2-hydroxy-1-naphthyl, 6-hydroxy-1,3-benzodioxol-5-yl, etc.] and 2-[(4,4-diarylbutyl)amino]pyrimidine by reactions of (hetero)aromatic C-nucleophiles with N-(4,4-diethoxybutyl)pyrimidin-2-amine in the presence of trifluoroacetic acid. The structures of the obtained products were confirmed by methods of IR spectroscopy, 1H and 13C NMR spectroscopy and X-ray structural anal. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Application of 95-88-5).
4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Application of 95-88-5
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics