Selective Synthesis of C1-Symmetric BINOL-phosphates and P-chiral Phosphoramides Using Directed ortho-Lithiation was written by Volpe, Rohan;Law, Hanson Y.-L.;White, Jonathan M.;Flynn, Bernard L.. And the article was included in Organic Letters in 2021.SDS of cas: 75-57-0 The following contents are mentioned in the article:
Directed ortho-lithiation (DoL) has been developed as an effective method for the ortho-substitution of BINOL-phosphoric acid and BINOL-N-triflylphosphoramide (BINOL-P-acids). It can be employed in the rapid assembly of either mono- or disubstituted BINOL-P-acids, including unsym. disubstitution through iterative DoL. Most significantly, DoL has proven to be highly effective in the diastereoselective desymmetrization of pseudo-C2-sym. BINOL-N-triflylphosphoramide, affording a chiral P-group. This study involved multiple reactions and reactants, such as Tetramethylammonium chloride (cas: 75-57-0SDS of cas: 75-57-0).
Tetramethylammonium chloride (cas: 75-57-0) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.SDS of cas: 75-57-0
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics