Pd(OAc)2-catalyzed tandem reactions for the synthesis of indol-3-yl substituted 1H-isochromenes and 1,2-dihydroisoquinolines was written by Wang, Huan;Han, Xiuling;Lu, Xiyan. And the article was included in Chinese Journal of Chemistry in 2011.Category: chlorides-buliding-blocks The following contents are mentioned in the article:
A Pd(II)-catalyzed tandem annulation of 2-(alkynyl)benzaldehyde derivatives or benzaldimines with indole derivatives by initial intermol. addition of the indoles to the carbonyl or imine group followed by the nucleopalladation of an intramol. alkyne and quenching of the C-Pd bond by protonolysis to regenerate the Pd(II) species was developed. The synthesis of the target compounds was achieved under mild reaction conditions, without the necessity of a redox system. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Category: chlorides-buliding-blocks).
5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Category: chlorides-buliding-blocks
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics