Cascade bicyclizations of o-alkynyl aldehydes with thiazolium salts: a new access toward poly-functionalized indeno[2,1-b]pyrroles was written by Zhou, Peng;Hao, Wen-Juan;Zhang, Jin-Peng;Jiang, Bo;Li, Guigen;Tu, Shu-Jiang. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2015.Computed Properties of C15H9ClO The following contents are mentioned in the article:
A new cascade bicyclization of o-alkynyl aldehydes with thiazolium salts is described, in which 25 examples of densely functionalized indeno[2,1-b]pyrroles I (Z = CH, N; R = Et, Me, Bn; R1 = H, 6-F, 6-Cl, 5-F; Ar = Ph, 4-MePh, 4-OMePh, 4-FPh, 4-ClPh, etc.) are achieved in a functional-group-compatible manner. Thiazole carbenes generated in situ from thiazolium salts play dual roles as reaction partners and as NHC catalysts. The synthetic utility of these bicyclization reactions results in subsequent C-C bond-forming events to rapidly build up mol. complexity. This study involved multiple reactions and reactants, such as 5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3Computed Properties of C15H9ClO).
5-Chloro-2-(phenylethynyl)benzaldehyde (cas: 1186603-47-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Computed Properties of C15H9ClO
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics