Gehling, Victor S. published the artcileDiscovery, Design, and Optimization of Isoxazole Azepine BET Inhibitors, Formula: C7H8BClO2, the publication is ACS Medicinal Chemistry Letters (2013), 4(9), 835-840, database is CAplus and MEDLINE.
The identification of a novel series of small mol. BET inhibitors is described. Using crystallog. binding modes of an amino-isoxazole fragment and known BET inhibitors, a structure-based drug design effort lead to a novel isoxazole azepine scaffold, e.g. I. This scaffold showed good potency in biochem. and cellular assays and oral activity in an in vivo model of BET inhibition.
ACS Medicinal Chemistry Letters published new progress about 209919-30-2. 209919-30-2 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Boronic acid and ester,Benzene,Boronic Acids,Boronic acid and ester, name is 4-Chloro-2-methylphenylboronic acid, and the molecular formula is C7H8BClO2, Formula: C7H8BClO2.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics