Mathew, Vinod published the artcileSynthesis, characterization and pharmacological activities of 3,6-disubstituted-1,2,4-triazolo [3,4-b]-1,3,4-thiadiazoles and their dihydro analogues, Quality Control of 6313-54-8, the publication is E-Journal of Chemistry (2007), 4(3), 320-342, database is CAplus.
4-Amino-5-aryl, or heteroaryl, substituted-3-mercapto-1,2,4-triazoles were prepared from the corresponding aromatic carboxylic acids through a multi-step sequence. These compounds were then reacted with various aromaticand hetero aromatic acids and hetero aromatic aldehydes to give 3,6-disubstituted-1,2,4-triazolo [3,4-b]-1,3,4-thiadizoles, e.g., I, and 3,6-disubstituted-5,6-dihydro-1,2,4-triazolo [3,4-b]-1,3,4-thiadizoles resp. Elemental anal., IR, 1H NMR and mass spectral data was elucidated for the structures of all newly synthesized compounds Synthesized compounds were studied for their antibacterial, antifungal, anti-inflammatory and analgesic activities. Some of the tested compounds showed significant pharmacol. activities.
E-Journal of Chemistry published new progress about 6313-54-8. 6313-54-8 belongs to chlorides-buliding-blocks, auxiliary class Pyridine,Chloride,Carboxylic acid, name is 2-Chloroisonicotinic acid, and the molecular formula is C6H4ClNO2, Quality Control of 6313-54-8.
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