Okawara, Tadashi published the artcileFacile synthesis of four-, five-, six-, and seven-membered heterocyclic compounds by the reaction of hydrazines and thiosemicarbazides with α- and β-halogenoacyl halides in a two-phase system, Application of 2,3-Dibromopropionylchloride, the publication is Journal of Chemical Research, Synopses (1987), 254-5, database is CAplus.
Phase-transfer cyclization of RNHNHR (I, R = Ph, Me) with R1CHXCOCl (II, R1 = H, X = Cl; R1 = Me, Et, Ph, X = Br) in the presence of PhCH2N+Et3 Cl– gave diazetidinones III (R2 = R) in 20-45% yields. Cyclization of thiosemicarbazides R3NHCSNHNH2 (R3 = Bu, cyclohexyl, PhCH2, Ph) with ClCH2COCl gave diazetidinones III [R = R1 = H, R2 = C(:NR3)SCOCH2Cl] in 52-84% yields. Similar cyclization of R4NHCSNMeNHMe (R4 = Ph, cyclohexyl, 1-naphthyl) with II gave thiadiazinone derivatives IV in 52-81% yields. Cyclization of I (R = Ph) with XCH2CR5R6COCl (V, R5 = H, Me, R6 = X = Br; R5 = R6 = Me, X = Cl) gave diphenylpyrazolinones VI. Phase-transfer cyclization of R7NHCSNR8NH2 (R7 = cyclohexyl, R8 = H, Me) with V (R5 = R6 = Me, X = Cl) gave 1,3,4-thiadiazepines, e.g. VII, along with azetidinone derivatives
Journal of Chemical Research, Synopses published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Application of 2,3-Dibromopropionylchloride.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics