Adarchenko, A. A. published the artcileSensitivity of clinical Pseudomonas aeruginosa strains to antiseptics, Safety of N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, the publication is Antibiotiki i Khimioterapiya (1989), 34(12), 902-7, database is CAplus and MEDLINE.
MICs, the frequency of clin. and statistic resistance, and the antiseptic activity index were studied in a complex of outpatient and hospital ecovars of P. aeruginosa. The forms resistant to a number of antiseptics, i.e., chloramine B, chlorhexidine, decamethoxine, and dioxidine, whose frequency eventually increased were shown to be widely distributed. The antiseptic sensitivity spectrum was more narrow and more heterogeneous than that of other bacteria, the heterogeneity level being dependent on the antiseptic type and bacterial ecovar. The activity of pervomur, phenol, resorcinol, and boric acid was high against the clin. strains of P. aeruginosa, while iodopyrine, sulfacetamide sodium, and dioxidine were less active. The P. aeruginosa strains had natural resistance to cetylpyridinium chloride roccal, ethonium, sodium laurate, SDS, and rivanol. It was recommended to assay antiseptic sensitivity of agents causing purulent inflammatory infections and to control circulation of antiseptic-resistant variants of bacteria in hospitals.
Antibiotiki i Khimioterapiya published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C38H74Cl2N2O4, Safety of N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride.
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