Hanson, J. C. published the artcileDerivatives of 6-aminopenicillanic acid. VIII. Further analogs of 3-o-chlorophenyl-5-methyl-4-isoxazolylpenicillin, Recommanded Product: 3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylic acid, the publication is Journal of the Chemical Society (1965), 5976-83, database is CAplus.
cf. CA 60, 5475c. Various analogs of 3-o-chlorophenyl-5-methylisoxazole-4-carboxylic acid containing addnl. substituents in the benzene ring have been synthesized. Chlorides of these acids, together with certain other dihalogen derivatives of 5-methyl-3-phenyl- and 3-methyl-5-phenylisoxazole-4-carbonyl chlorides, were condensed with 6-aminopenicillanic acid to give new penicillins with useful anti-bacterial properties.
Journal of the Chemical Society published new progress about 3919-74-2. 3919-74-2 belongs to chlorides-buliding-blocks, auxiliary class Isoxazole,Fluoride,Chloride,Carboxylic acid,Benzene, name is 3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylic acid, and the molecular formula is C11H7ClFNO3, Recommanded Product: 3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylic acid.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics