Liu, Yue-Jin published the artcileCopper/Silver-Mediated Direct ortho-Ethynylation of Unactivated (Hetero)aryl C-H Bonds with Terminal Alkyne, Related Products of chlorides-buliding-blocks, the publication is Chemistry – A European Journal (2015), 21(1), 205-209, database is CAplus and MEDLINE.
A copper/silver-mediated oxidative ortho-ethynylation of unactivated aryl C-H bonds with terminal alkynes has been developed. The reaction uses the removable PIP [PIP = 2-(pyridin-2-yl)isopropyl] directing group and features broad substrate scope, high functional-group tolerance, and compatibility with a wide range of heterocycles, providing an efficient synthesis of aryl alkynes. E.g., Cu(OAc)2 and Ag2CO3 catalyzed the ethynylation of benzene derivative (I) with CHCTIPS to give 42% II. This procedure highlights the potential of copper catalysts to promote unique synthetically enabling C-H functionalization reactions that lie outside of the current scope of precious metal catalysis.
Chemistry – A European Journal published new progress about 6313-54-8. 6313-54-8 belongs to chlorides-buliding-blocks, auxiliary class Pyridine,Chloride,Carboxylic acid, name is 2-Chloroisonicotinic acid, and the molecular formula is C6H4ClNO2, Related Products of chlorides-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics