Wang, Xin published the artcileControlling cyclization pathways in palladium(II)-catalyzed intramolecular alkene hydro-functionalization via substrate directivity, Safety of ((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride, the publication is Chemical Science (2020), 11(41), 11307-11314, database is CAplus and MEDLINE.
The palladium(II)-catalyzed, intramol. alkene hydrofunctionalization reactions with carbon, nitrogen, and oxygen nucleophiles formed five- and six-membered carbo- and heterocycles. In these reactions, the presence of a proximal bidentate directing group controlled the cyclization pathway, dictating the ring size that was generated, even in cases that are disfavored based on Baldwin’s rules and in cases where there is an inherent preference for an alternative pathway. DFT studied shed light on the origins of pathway selectivity in these processes.
Chemical Science published new progress about 21286-54-4. 21286-54-4 belongs to chlorides-buliding-blocks, auxiliary class Chiral,Chloride,Sulfonyl chlorides,Aliphatic cyclic hydrocarbon,Ketone, name is ((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride, and the molecular formula is C8H5F3O2S, Safety of ((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride.
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