Doyle, F. P. published the artcileDerivatives of 6-aminopenicillanic acid. V. Analogs of 2,6-dimethoxyphenylpenicillin with enhanced stability towards acids, Application of 3-Chloro-2,6-dimethoxybenzoic acid, the publication is Journal of the Chemical Society (1963), 497-506, database is CAplus.
Various derivatives of 2,6-dimethoxybenzoic acid containing electron-attracting substituents elsewhere in the ring have been synthesized. Analogs in which one or both of the methoxy groups have been replaced by other substituents have also been prepared Reaction of the acid chlorides with 6-aminopenicillanic acid gave penicillins which were less readily inactivated by acid than 2,6-dimethoxyphenylpenicillin. The stability at low pH increased with increasing strength of the side-chain acids.
Journal of the Chemical Society published new progress about 36335-47-4. 36335-47-4 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Carboxylic acid,Benzene,Ether, name is 3-Chloro-2,6-dimethoxybenzoic acid, and the molecular formula is C9H9ClO4, Application of 3-Chloro-2,6-dimethoxybenzoic acid.
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https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics