Hwang, Soo-Yeon published the artcileField-based rational design of p300 histone acetyltransferase inhibitor and systematic evaluation as an anti-fibrotic agent, Recommanded Product: 3-Chlorobenzylchloride, the publication is Chemical Communications (Cambridge, United Kingdom) (2020), 56(68), 9795-9798, database is CAplus and MEDLINE.
(E)-3-(3-(4-((3-Carbamoylbenzyl)oxy)-3-iodo-5-methoxyphenyl) acryloyl)benzamide (A6) was found to be a potent p300 inhibitor (IC50 = 870 nM) showing a similar binding mode to that of acetyl-CoA, a p300 substrate, and effective anti-fibrotic activity in both TGF-β1-stimulated lung fibroblast cells and bleomycin-induced in vivo lung fibrosis mice.
Chemical Communications (Cambridge, United Kingdom) published new progress about 620-20-2. 620-20-2 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 3-Chlorobenzylchloride, and the molecular formula is C7H6Cl2, Recommanded Product: 3-Chlorobenzylchloride.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics