Mal, Sanjib published the artcileFacile one pot synthesis of 8-chloro-[1,2,4]triazolo[4,3-a]pyrazines via oxidative cyclisation using chloramine T, Category: chlorides-buliding-blocks, the publication is Tetrahedron Letters (2015), 56(22), 2896-2901, database is CAplus.
A facile and expedient one pot synthesis of 8-chloro-[1,2,4]triazolo[4,3-a]pyrazine derivatives I [R1 = H, Cl; R = Ph, 3-MeO-C6H4, 4-Br-C6H4, etc.] from 2-chloro-3-hydrazinylpyrazine and aldehydes is described using chloramine T trihydrate as a safe and convenient electrocyclisation (oxidising) agent. The presence of the chloro group on pyrazine enabled us to access versatile new synthetic scaffolds II [R1 = Ph, 2-thiophenyl, 2,4-diCl-C6H3] by easy diversification using palladium catalyzed Suzuki-Miyaura and Sonogashira cross coupling reactions. The products are obtained in high yields in short reaction time under mild conditions without the need for chromatog. purification
Tetrahedron Letters published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Category: chlorides-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics