Villieras, J.’s team published research in Synthesis in | CAS: 866-23-9

Synthesis published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C18H35NO, SDS of cas: 866-23-9.

Villieras, J. published the artcileSimple route from aldehydes to alkynes and 1-chloro-1-alkynes, SDS of cas: 866-23-9, the publication is Synthesis (1975), 458-61, database is CAplus.

Reaction of RCHO (R = e.g., Et2CH, cyclohexyl, MeCH:CH, PhCH:CH, substituted phenyl) with LiCCl2P(O)(OEt)2 in THF-ether gave 85-90% RCH:CCl2 which 1) with LiNEt2 in THF-ether gave RCCCl and 2) with EtLi or BuLi in THF-ether at -10 to -70° gave RCCLi which was hydrolyzed with aqueous H2SO4 to RCCH or alkylated with chlorodimethyl ether to give methoxymethyl derivatives (e.g., 1-cyclohexyl-3-methoxy-1-propyne).

Synthesis published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C18H35NO, SDS of cas: 866-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics