Villieras, Jean’s team published research in Synthesis in | CAS: 866-23-9

Synthesis published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C7H8BNO4, Category: chlorides-buliding-blocks.

Villieras, Jean published the artcileα-Chloroenolates; VI. Diethyl 1-chloro-1-lithio-2-oxoalkanephosphonates; synthesis of α-chloro-α,β-unsaturated ketones, Category: chlorides-buliding-blocks, the publication is Synthesis (1978), 29-31, database is CAplus.

1-Chloro-2-oxoalkanephosphonates RCOCHClP(O)(OEt)2 (I; R = Pr, iso-Pr, tert-Bu) were prepared in 60-85% yield by treating LiCCl2P(O)(OEt)2 with BuLi at -90° followed by acylation with RCOCl at -125 and hydrolysis. In situ reaction of I α-Li derivatives with aldehydes R1CHO (R1 = Ph, 2- or 4-ClC6H4, Bu) gave α,β-unsaturated ketones (E)-R1CH:CClCOR.

Synthesis published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C7H8BNO4, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics