Vislohuzova, Tetiana published the artcileStudy of biodegradation, biocompatibility and bactericidal activity of film materials with tiamulin fumarate based on polyurethaneurea, Related Products of chlorides-buliding-blocks, the publication is Chemistry & Chemical Technology (2020), 14(3), 318-326, database is CAplus.
The influence of the model biol. medium 199 on the structure and properties of film materials with tiamulin fumarate based on polyurethaneurea containing in its structure the hydrophilic fragments of the copolymer of N-vinylpyrrolidone with vinyl acetate and vinyl alc. has been investigated. According to IR spectroscopy, under the influence of the biol. medium 199 there are processes of biodegradation of polymer materials which are accompanied by a decrease in the intensity of the absorption band νC=O of vinylpyrrolidone ring. It is established that the introduction of tiamulin fumarate into polyurethaneurea facilitates their biodegradation, as evidenced by a decrease of the tensile strength (1.28-2.38 times) and a relative elongation at break (1.36-1.82 times) after incubation in the biol. medium 199 by physico-mech. tests. The tissue culture method has established the biocompatibility of film materials with tiamulin fumarate. According to the results of microbiol. studies, bactericidal properties were observed in relation to the bacteria Staphylococcus aureus and Escherichia coli. It allows using them for production of drainage in abdominal surgery.
Chemistry & Chemical Technology published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C4H6O3, Related Products of chlorides-buliding-blocks.
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