He, Renbao published the artcileSynthesis of 2,4,5-trifluorobenacetic acid, Quality Control of 243139-71-1, the publication is Huagong Shengchan Yu Jishu (2011), 18(3), 4-6, database is CAplus.
The compound 2,4,5-trifluorobenzeneacetic acid was synthesized from 1,2,4-trifluorobenzene via chloromethylation, carbonylation and hydrolyzation. Results showed that the optimization synthesis condition of 2,4,5-trifluorobenzyl chloride were as follows: m (C6H3F3):m (paraformaldehyde)=1.0:0.875-0.865, reaction time 10 h. And the optimization synthesis condition of 2,4,5-trifluorobenzeneacetic acid was m (C7H4F3Cl): m (cat)=1:0.275-0.25 and the reaction temperature was 40°C, under this condition, the total yield was above 60%, the purity was above 99%. The proportion of reactants and dosage of catalyst were discussed.
Huagong Shengchan Yu Jishu published new progress about 243139-71-1. 243139-71-1 belongs to chlorides-buliding-blocks, auxiliary class Fluoride,Chloride,Benzyl chloride,Benzene, name is 2,4,5-Trifluorobenzyl chloride, and the molecular formula is C7H4ClF3, Quality Control of 243139-71-1.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics