Lin, Lian-Fang published the artcileSyntheses of methadone and 5-nitrofurfural, Recommanded Product: 2-Chloro-N,N-dimethylpropan-1-amine hydrochloride, the publication is Bulletin of the Institute of Chemistry, Academia Sinica (1980), 13-17, database is CAplus.
EtCOCPh2CH2CHMeNMe2 (I), was prepared from ClCH2CHMeOH (II) in 4 steps. Thus, amination of II with Me2NH and subsequent SOCl2 chlorination gave Me2NCH2CHClMe, which condensed with Ph2CHCN in aqueous NaOH to give Ph2C(CN)CH2CHMeNMe2. Reaction of the latter with EtMgBr and subsequent hydrolysis gave I. Nitration of furfural by HNO3-H2SO4 in Ac2O gave 2-(diacetoxymethyl)-5-nitrofuran, which was treated with 73% H2SO4 to give 5-nitrofurfural, an intermediate in the preparation of furazolidone.
Bulletin of the Institute of Chemistry, Academia Sinica published new progress about 4584-49-0. 4584-49-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Salt,Amine,Aliphatic hydrocarbon chain, name is 2-Chloro-N,N-dimethylpropan-1-amine hydrochloride, and the molecular formula is C5H13Cl2N, Recommanded Product: 2-Chloro-N,N-dimethylpropan-1-amine hydrochloride.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics