Sasaki, Shigeru published the artcileBisoxazoline-catalyzed asymmetric nucleophilic addition of diethyl zinc to fluorinated alkyl ketones: enantiofacial control by changing the bisoxazoline substituent, Application of 1-(2-Chlorophenyl)-2,2,2-trifluoroethanone, the publication is Bulletin of the Chemical Society of Japan (2015), 88(1), 200-208/1-200-208/9, 9 pp., database is CAplus.
Bisoxazoline (BOX)-catalyzed asym. nucleophilic addition of di-Et zinc to fluorinated alkyl ketones successfully afforded enantioenriched fluorinated alkyl tertiary alcs. The effect of the size of the substituent on the oxazoline ring on the stereoselectivity of the reaction was investigated. Furthermore, the enantioselectivity could be reversed by altering the BOX bridge structure while retaining the C-4 substituent on the oxazoline ring.
Bulletin of the Chemical Society of Japan published new progress about 5860-95-7. 5860-95-7 belongs to chlorides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Chloride,Benzene,Ketone, name is 1-(2-Chlorophenyl)-2,2,2-trifluoroethanone, and the molecular formula is C8H4ClF3O, Application of 1-(2-Chlorophenyl)-2,2,2-trifluoroethanone.
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