Senaweera, Sameera published the artcileSNAr catalysis enhanced by an aromatic donor-acceptor interaction; facile access to chlorinated polyfluoroarenes, Name: N-Benzyl-N,N-dibutylbutan-1-aminium chloride, the publication is Chemical Communications (Cambridge, United Kingdom) (2017), 53(54), 7545-7548, database is CAplus and MEDLINE.
Selective catalytic SNAr reaction of polyfluoroaryl C-F bonds with chloride is shown. Stoichiometric TMSCl makes the reaction exergonic and allows catalysis, which involves ground state elevation of chloride, aromatic donor-acceptor interactions, and stabilization of the Meisenheimer complex. Traditional cross-coupling of the products is now possible and demonstrates the utility. Thus, e.g., treatment of pentafluoropyridine with TMSCl and benzyltributylammonium chloride afforded 4-chloro-2,3,5,6-tetrafluoropyridine (95%).
Chemical Communications (Cambridge, United Kingdom) published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C2H2N4O2, Name: N-Benzyl-N,N-dibutylbutan-1-aminium chloride.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics