Sun, Caocao published the artcileIntegrating aryl chlorides into nickel-catalyzed 1,1-difunctionalization of alkenes, Product Details of C12H15ClO3, the publication is Chinese Chemical Letters (2022), 33(12), 5096-5100, database is CAplus.
Herein, a first achievement in 1,1-difunctionalization of alkenes RCH=CH2 (R = hexyl, cyclohexyl, 3-(1H-pyrrol-1-yl)propyl, 9H-carbazol-9-ylmethyl, etc.) with aryl chlorides ArCl (Ar = Ph, 2,4-difluorophenyl, 1-[(tert-butoxy)(oxo)methane]-1H-indol-6-yl, 2H-1,3-benzodioxol-5-yl, etc.) as coupling partners was reported. The success is predominantly ascribed to the judicious selection of 1,2-diamine ligand. This study provides an efficient protocol for the synthesis of secondary benzyl boronates RCH2CH(R1)Ar (R1 = tetramethyl-1,3,2-dioxaborolan-2-yl) from easily accessible feedstock chems. Furthermore, the distinguished features of this method include excellent 1,1-regio- and chemoselectivity, good functional group tolerance and easily-operational catalytic reaction conditions.
Chinese Chemical Letters published new progress about 637-07-0. 637-07-0 belongs to chlorides-buliding-blocks, auxiliary class Inhibitor,Cell Cycle,PPAR, name is Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate, and the molecular formula is C13H15NO6S, Product Details of C12H15ClO3.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics