Wu, Hsyueh-Liang published the artcileEnantioselective addition of organozinc reagents to carbonyl compounds catalyzed by a camphor derived chiral γ-amino thiol ligand, Category: chlorides-buliding-blocks, the publication is Tetrahedron (2016), 72(21), 2656-2665, database is CAplus.
The design and synthesis of the chiral camphor derived γ-amino thiol ligand I and its application in catalytic enantioselective carbon-carbon forming reactions through the addition of organozinc reagents (R)2Zn (R = Me, Et) to carbonyl compounds R1CHO (R1 = 2-ClC6H4, 2-thienyl, cyclohexyl, etc.) have been described. The catalytic activity and enantioselectivity of ligand I were demonstrated in the enantioselective addition of various organozinc reagents to aldehydes and ketoesters ArC(O)CO2CH3 (Ar = 2-H3CC6H4, 2-furyl, 2-naphthyl, etc.), offering the corresponding alcs. e.g., 4-BrC6H4CH(OH)CH3 in high yields and enantioselectivities. The role of the mercapto group in the highly enantioselective 1,2-addition reaction of organozincs to aldehyde was also discussed.
Tetrahedron published new progress about 21286-54-4. 21286-54-4 belongs to chlorides-buliding-blocks, auxiliary class Chiral,Chloride,Sulfonyl chlorides,Aliphatic cyclic hydrocarbon,Ketone, name is ((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride, and the molecular formula is C7H11N, Category: chlorides-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics