Yuan, Huihui published the artcileA solvent-free method for the preparation of phosphinates from P(O)-OH compounds with alkyl chlorides, Name: 3-Chlorobenzylchloride, the publication is Tetrahedron Letters (2021), 153529, database is CAplus.
Herein, a new solvent-free synthetic method using P(O)-OH compound and alkyl chloride for phosphinate compounds is disclosed. This transformation proceeds smoothly under the promotion of a lone base and presents the advantages of an easily available raw material source, a simple post treatment process, good functional group tolerance and high reaction efficiency. Good yield was obtained when the reaction was magnified to gram scale(coating), and the molar ratio of P(O)-OH compounds and alkyl chlorides can be decreased to 1:2. This protocol provides a practical method for the preparation of phosphorus derivatives Furthermore, the reaction mechanism was explored by 31P NMR.
Tetrahedron Letters published new progress about 620-20-2. 620-20-2 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 3-Chlorobenzylchloride, and the molecular formula is C9H13NO2, Name: 3-Chlorobenzylchloride.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics