Akusoba, E. U. published the artcile6-Coumarinsulfonyl chloride (6CSCL): a fluorescent label for protein molecules, SDS of cas: 10543-42-7, the publication is Fresenius’ Zeitschrift fuer Analytische Chemie (1985), 320(2), 182-3, database is CAplus.
Albumin and γ-globulin were labeled with 6CSCL, purified by gel chromatog. on Sephadex G 25, and the fluorescence and other properties of the labeled proteins were studied. The fluorescence intensity of labeled albumin decreased slightly with increasing temperature and increased sharply with increasing pH. An increase in dielec. constants of solvents was accompanied by a bathochromic shift in fluorescence maximum for labeled γ-globulin. Freeze-dried conjugate lost no fluorescence intensity after refrigeration for 2 wk. 6CSCL resembles dansyl chloride in its reactions and is a promising cheap and stable label for proteins and amino acids.
Fresenius’ Zeitschrift fuer Analytische Chemie published new progress about 10543-42-7. 10543-42-7 belongs to chlorides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Chloride,Sulfonyl chlorides,Ester, name is Coumarin-6-sulfonyl chloride, and the molecular formula is C9H5ClO4S, SDS of cas: 10543-42-7.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
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