Fu, Jun-Hao published the artcileEnantioselective vinylogous aldol/lactonization cascade reaction between β,γ-unsaturated amides and trifluoromethyl ketones: facile access to chiral trifluoromethyl dihydropyranones, Safety of 1-(2-Chlorophenyl)-2,2,2-trifluoroethanone, the publication is Organic & Biomolecular Chemistry (2020), 18(39), 7848-7851, database is CAplus and MEDLINE.
An efficient asym. vinylogous aldol/lactonization cascade reaction between β,γ-unsaturated amides I (R1 = C6H5, 2-thienyl, 1-naphthyl, etc.) and trifluoromethyl ketones has R2C(O)CF3 (R2 = C6H5, 2-ClC6H4, CH=CHC6H5, etc.) been developed. Using a chiral cyclohexanediamine-based tertiary amine-thiourea catalyst II [Ar = 3,5-(CF3)2C6H3], optically active trifluoromethyl dihydropyranones (S)-III have been constructed in moderate-to-excellent yields (up to 99%) with excellent stereoselectivities (96-> 99.5% ee).
Organic & Biomolecular Chemistry published new progress about 5860-95-7. 5860-95-7 belongs to chlorides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Chloride,Benzene,Ketone, name is 1-(2-Chlorophenyl)-2,2,2-trifluoroethanone, and the molecular formula is C8H4ClF3O, Safety of 1-(2-Chlorophenyl)-2,2,2-trifluoroethanone.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics