Herbain, Maurice published the artcileA biologic test of antilipemic heparin derivatives, Recommanded Product: 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, the publication is Clinica Chimica Acta (1960), 204-7, database is CAplus and MEDLINE.
cf. Velluz, et al., CA 53, 10555g, 19898g. Rabbits were fed a diet containing saturated fats and 200 mg./kg./day cholesterol for a period of 30 days. Those animals in which serum total cholesterol levels reached 8 g./l. or more were selected for testing. The ratio of β-lipoprotein lipide/total lipide exceeded 0.70 compared to a control value of 0.35. After removal of cholesterol from the diet for 24 hrs., 5 mg./kg. heparin or other antilipemic agent was injected intravenously and total and β-lipoprotein lipides (the latter were precipitated with dextran) were estimated at 6, 10, and 14 hrs. When the test was carried out with N-dimethylbenzoyl-N-desulfoheparin, its antilipemic activity was found to be slower but more intense than that of heparin.
Clinica Chimica Acta published new progress about 6249-56-5. 6249-56-5 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst,Inhibitor,Natural product, name is 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, and the molecular formula is C7H16ClNO2, Recommanded Product: 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics