Qu, Shuhao published the artcileDesign, synthesis and insecticidal activity of 3-arylisoxazoline-N-alkylpyrazole-5-carboxamide derivatives against Tetranychus urticae koch, Category: chlorides-buliding-blocks, the publication is Heterocycles (2022), 104(3), 512-523, database is CAplus.
Starting from Et 5,5-dimethoxy-2,4-dioxopentanoate 2,3-arylisoxazoline-N-alkylpyrazole-5-carboxamide derivatives I (R = HNCH2C(O)NHCH2CF3, 4-t-BuC6H4CH2NH, 4-EtOC6H4CH2NH, 4-MeC6H4OC6H4CH2NH) were designed and synthesized with the key steps of 1,3-dipolar cycloaddition and EDCl coupling. Their insecticidal activity against Tetranychus urticae Koch was further evaluated and the results indicated that, compared with Fluralaner, all compounds showed moderate and less activity at 500 mg/L and 250 mg/L, resp. This study complements the structure-activity relationship of N-alkylpyrazole-5-carboxamides to Fluralaner, giving further guidance in Fluralaner-based pesticide drug design and discovery.
Heterocycles published new progress about 864725-22-4. 864725-22-4 belongs to chlorides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Chloride,Alkenyl,Benzene, name is 1,3-Dichloro-5-(3,3,3-trifluoroprop-1-en-2-yl)benzene, and the molecular formula is C9H5Cl2F3, Category: chlorides-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics