Volyanskii, Y. L. published the artcileEffect of decametoxin, some quinoline and phenol derivatives on the main growth and propagation parameters of Staphylococci and Escherichia coli., Quality Control of 38146-42-8, the publication is Trudy – Tomskii Nauchno-Issledovatel’skii Institut Vaktsin i Syvorotok, Tomskii Meditsinskii Institut [i] Tomskoe Otdelenie Vserossiiskogo Nauchno-Meditsinskogo Obshchestva Mikrobiologov, Epidemiologov i Parazitologov (1981), 260-3, database is CAplus.
While minimal concentrations of decametoxin and of a quinoline deriv (comp. 264) initially gradually decreased the optical d. of staphylococcal cultures and those of coliform bacteria, a Cl-containing phenolic compound (compound 492) caused no changes in the optical d. of the cultures. However, between the second and fourth h of incubation in presence of first 2 compounds the level of optical d. was stabilized and thereafter increased, the increase being associated with increasing rate of biomass accumulation in the exponential phase. The increase in staphylococcal biomass at that phase under the action of decametoxin at subbacteriostatic concentration was slower than that at min. inhibitory concentration The lag-phase in control and in the presence of the first 2 compounds at bacteriostatic and subbacteriostatic concentrations was the same, while at similar concentrations compound 492 increased the lag-phase ∼2-fold. Compound 492 at min. bacteriostatic and subbacteriostatic rates was neutral with regard to substrate utilization by Escherichia coli, while the first 2 compounds by activating and inducing enzymic systems in the bacteria permitted utilizing the carbohydrates present in the medium, which probably resulted in the intensive biomass increment observed in the exponential phase.
Trudy – Tomskii Nauchno-Issledovatel’skii Institut Vaktsin i Syvorotok, Tomskii Meditsinskii Institut [i] Tomskoe Otdelenie Vserossiiskogo Nauchno-Meditsinskogo Obshchestva Mikrobiologov, Epidemiologov i Parazitologov published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C20H28B2O4S2, Quality Control of 38146-42-8.
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