Yang, Tonghao published the artcileCopper-catalyzed radical reactions of 2-azido-N-arylacrylamides with 1-(trifluoromethyl)-1,2-benziodoxole and 1-azidyl-1,2-benziodoxole, Related Products of chlorides-buliding-blocks, the publication is Organic & Biomolecular Chemistry (2016), 14(13), 3376-3384, database is CAplus and MEDLINE.
The reactions of 2-azido-N-arylacrylamides with trifluoromethyl radicals and azidyl radicals were investigated by using Togni’s reagent and Zhdankin’s reagent as the source of these radicals. Under the catalysis of CuI, Togni’s reagent was firstly converted into the trifluoromethyl radical, which then reacted with 2-azido-N-arylacrylamides to afford the corresponding α-(arylaminocarbonyl)iminyl radicals. The cyclization of the iminyl radicals delivered quinoxalin-2(1H)-one products in moderate yields. A similar reaction took place between 2-azido-N-arylacrylamides and the azidyl radical. In the latter cases, the reaction produced 3-azidomethyl and 3-cyano-substituted quinoxalin-2(1H)-ones. This study not only helps to elucidate the factors influencing the cyclization of α-(arylaminocarbonyl)iminyl radicals, but also provided a new approach towards quinoxalin-2-ones.
Organic & Biomolecular Chemistry published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C26H26N4O7, Related Products of chlorides-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics