Zeng, Hao published the artcileThree component hydroxyletherification and hydroxylazidation of (trifluoromethyl)alkenes: access to α-trifluoromethyl β-heteroatom substituted tertiary alcohols, SDS of cas: 864725-22-4, the publication is Chemical Communications (Cambridge, United Kingdom) (2020), 56(46), 6241-6244, database is CAplus and MEDLINE.
The three component hydroxyletherification and hydroxylazidation reactions of (trifluoromethyl)alkenes RC(=CH2)CF3 (R = Ph, 2H-1,3-benzodioxol-5-yl, naphthalen-2-yl, etc.) are reported, providing various useful α-trifluoromethyl β-heteroatom substituted tertiary alcs. e.g., I in high yields. The ipso-defluorooxylation of (trifluoromethyl)alkenes with oximes e.g., 2-phenyl-3,3,3-trifluoropropene is completely inhibited. A pesticidal active compound could be synthesized with this method.
Chemical Communications (Cambridge, United Kingdom) published new progress about 864725-22-4. 864725-22-4 belongs to chlorides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Chloride,Alkenyl,Benzene, name is 1,3-Dichloro-5-(3,3,3-trifluoroprop-1-en-2-yl)benzene, and the molecular formula is C6H3ClFNO2, SDS of cas: 864725-22-4.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics