Nagarajan, K. published the artcileAntiimplantation agents: part I – 1-arylthiosemicarbazides, Formula: C7H6ClF3N2, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1984), 23B(12), 1243-57, database is CAplus.
1-Arylthiosemicarbazides, 2-arylhydrazinothiazolines and 2-arylhydrazinodihydrothiazines were prepared and examined for their antiimplantation activity in rats. Among the active compounds, MeNHCSNHNHC6H3(CF3)2-3,5 (C2696-Go) and the corresponding 4,4-di-Me, Et, n-Bu, and allyl derivatives completely inhibit implantation at doses of 10, 3, 20, 20 and 30 mg/kg resp. The 3,4-dichlorophenyl analog is effective at a dose of 30 mg/kg. Hydrazinothiazoline I (n = 1) and the corresponding dihydrothiazine I (n = 2) show a weaker activity. The biol. profile of C2696-Go was determined and it prevents implantation by its antiuretotropic activity and ability to inhibit desiduoma formation.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 1869-22-3. 1869-22-3 belongs to chlorides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Chloride,Hydrazine,Amine,Benzene, name is 1-(2-Chloro-5-(trifluoromethyl)phenyl)hydrazine, and the molecular formula is C7H6ClF3N2, Formula: C7H6ClF3N2.
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https://en.wikipedia.org/wiki/Chloride,
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