Synthesis of polynuclear heterocycles. Part 4. imidazo[4,5-g][3,1]benzoxazinones, imidazo[4,5-g]quinazolinones, imidazo[4,5-g]quinazolinediones, and imidazo[4,5-f]indazolinones was written by Alkhader, Mohamed A.;Perera, R. Clinton;Sinha, Rajeshwar P.;Smalley, Robert K.. And the article was included in Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) in 1979.Recommanded Product: Ethyl 4-chloro-3-nitrobenzoate This article mentions the following:
Several 1,2-disubstituted 6-aminobenzimidazole-5-carboxylic acids and their Et esters were prepared in several steps from 4,3-Cl(O2N)C6H3CO2Et. The amino acids reacted with acyl halides in pyridine to give 7-arylimidazo[4,5-g][3,1]benzoxazin-5-ones, with urea or KCN to give imidazo[4,5-g]quinazoline-5,7-diones, and with HCONH2 to give imidazo[4,5-g]quinazolin-5-ones. 6-Amino- and 6-(acylamino)imidazo[4,5-g]quinazolin-5-ones were prepared by treating the acylated amino esters with N2H4, or by cyclizing the derived aminohydrazides with an acylating agent. Imidazo[4,5-f]indazolin-5-ones were obtained by the action of ethanolic N2H4.H2O on 6-azido-5-ethoxycarbonylbenzimidazoles. In the experiment, the researchers used many compounds, for example, Ethyl 4-chloro-3-nitrobenzoate (cas: 16588-16-2Recommanded Product: Ethyl 4-chloro-3-nitrobenzoate).
Ethyl 4-chloro-3-nitrobenzoate (cas: 16588-16-2) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Recommanded Product: Ethyl 4-chloro-3-nitrobenzoate
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics