A catalysis-driven artificial molecular pump was written by Amano, Shuntaro;Fielden, Stephen D. P.;Leigh, David A.. And the article was included in Nature (London, United Kingdom) in 2021.COA of Formula: C21H15Cl3O2 This article mentions the following:
All biol. pumps are autonomous catalysts; they maintain the out-of-equilibrium conditions of the cell by harnessing the energy released from their catalytic decomposition of a chem. fuel. A number of artificial mol. pumps have been reported to date, but they are all either fueled by light or require repetitive sequential additions of reagents or varying of an elec. potential during each cycle to operate. Here we describe an autonomous chem. fueled information ratchet that in the presence of fuel continuously pumps crown ether macrocycles from bulk solution onto a mol. axle without the need for further intervention. The mechanism uses the position of a crown ether on an axle both to promote barrier attachment behind it upon threading and to suppress subsequent barrier removal until the ring has migrated to a catchment region. Tuning the dynamics of both processes enables the mol. machine to pump macrocycles continuously from their lowest energy state in bulk solution to a higher energy state on the axle. The ratchet action is exptl. demonstrated by the progressive pumping of up to three macrocycles onto the axle from bulk solution under conditions where barrier formation and removal occur continuously. The out-of-equilibrium [n]rotaxanes (characterized with n up to 4) are maintained for as long as unreacted fuel is present, after which the rings slowly de-thread. The use of catalysis to drive artificial mol. pumps opens up new opportunities, insights and research directions at the interface of catalysis and mol. machinery. In the experiment, the researchers used many compounds, for example, 3,3,3-Tris(4-chlorophenyl)propionic acid (cas: 2168-06-1COA of Formula: C21H15Cl3O2).
3,3,3-Tris(4-chlorophenyl)propionic acid (cas: 2168-06-1) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.COA of Formula: C21H15Cl3O2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics