Synthesis of quinoxaline derivatives from benzofuroxan (Part II) was written by Kim, Ho Sik;Hur, Jae Hyuck. And the article was included in Journal of the Korean Chemical Society in 2005.HPLC of Formula: 6834-42-0 This article mentions the following:
Synthesis of 2-ethoxycarbonyl-3-methylquinoxaline 1,4-dioxide (I) from benzofuroxan and Et acetoacetate was accomplished. The reaction of compound I with hydrazine hydrate gave 2-hydrazinocarbonyl-3-methylquinoxaline 1,4-dioxide (II). The reactions of compound II with substituted phenylacetyl chlorides, benzyl chloroformate, heteroaryl aldehydes and acid anhydrides afforded 3-methyl-2-(substituted hydrazinocarbonyl)quinoxaline 4-oxides III [R = H, OMe], IV, V [X = O, S] and VI [R = Me, ethyl], resp. The reaction of compound II with isothiocyanates afforded 3-methyl-2-[(N-substituted thiocarbamoyl)hydrazinocarbonyl]quinoxaline 4-oxides VII [e.g., R = methyl], and followed reflux in 2N NaOH resulted in the intramol. cyclization to give 3-methyl-2-(4-substituted-3-thioxo-1,2,4-triazol-5-yl)quinoxaline 4-oxides VIII [e.g., R = methyl]. The herbicidal and fungicidal activities of the synthesized compounds were investigated. In the experiment, the researchers used many compounds, for example, 2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0HPLC of Formula: 6834-42-0).
2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.HPLC of Formula: 6834-42-0
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics