The synthesis of chiral 3-oxo-6-[(phenylmethoxy)carbonyl]-2-piperazineacetic acid esters designed for the presentation of an aspartic acid side chain. A subsequent novel Friedel Crafts reaction was written by Kogan, Timothy P.;Rawson, Thomas E.. And the article was included in Tetrahedron Letters in 1992.Application In Synthesis of 2-(3-Methoxyphenyl)acetyl chloride This article mentions the following:
The synthesis of the title esters (2S,6R)-I and (2S,6S)-I from
2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Application In Synthesis of 2-(3-Methoxyphenyl)acetyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics