Quantitative structure-activity relationships and mixture toxicity studies of heterocyclic nitrogen compounds was written by Chen, J.;Liao, Y.;Zhao, Y.;Wang, L.;Lu, G.;Zhao, T.. And the article was included in Bulletin of Environmental Contamination and Toxicology in 1996.Safety of 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine The following contents are mentioned in the article:
The toxicity of 13 heterocyclic nitrogen compounds to Daphnia magna and the resultant QSARs of these chems. based on the measured logKow values were reported. Mixture toxicities were also reported. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4Safety of 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine).
4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Safety of 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics