Palladium-Catalyzed meta-Selective C-H Alkenylation and Acetoxylation of Arylacetic Acid Using a Pyrimidine Template was written by Jiao, Bo;Peng, Zhen;Dai, Zhen-Hua;Li, Lei;Wang, He;Zhou, Ming-Dong. And the article was included in European Journal of Organic Chemistry in 2019.Application of 6834-42-0 This article mentions the following:
In the presence of Pd(OAc)2 and N-acetylglycine, pyrimidinylphenyl esters of arylacetic acids such as I underwent regioselective meta-selective alkenylation reactions with electron-deficient alkenes such as Et acrylate mediated by Ag2CO3 in hexafluoroisopropanol to yield alkenylarylacetate esters such as II. Using PhI(OAc)2 as oxidant and Ac2O, four of the pyrimidinylphenyl esters underwent regioselective acetoxylation to yield acetoxyphenylacetates. The pyrimidinylphenyl moiety was readily removable from the products and recovered. In the experiment, the researchers used many compounds, for example, 2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0Application of 6834-42-0).
2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Application of 6834-42-0
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics