A convenient synthesis of γ,δ-unsaturated N-formyl enamines by Wittig alkenylation of γ,δ-unsaturated diformamides was written by Van Vliet, Michiel C. A.;Meuzelaar, Gerrit J.;Bras, Jerome;Maat, Leendert;Sheldon, Roger A.. And the article was included in Liebigs Annalen/Recueil in 1997.Electric Literature of C25H21Cl2P This article mentions the following:
γ,δ-Unsaturated N-formyl enamines were prepared in 2 steps from readily available γ,δ-unsaturated alcs. The alcs. were converted into the γ,δ-unsaturated diformamides by tosylation, followed by reaction with NaN(CHO)2. The γ,δ-unsaturated diformamides were applied in a Wittig reaction under mild conditions to give the title compounds with a conjugated enamide group in moderate to high yields. In the experiment, the researchers used many compounds, for example, (2-Chlorobenzyl)triphenylphosphonium chloride (cas: 18583-55-6Electric Literature of C25H21Cl2P).
(2-Chlorobenzyl)triphenylphosphonium chloride (cas: 18583-55-6) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Electric Literature of C25H21Cl2P
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics