Synthesis and Crystal Structure of Benzoyloxymethyl (4α,8β,13β)-13-methyl-16-oxo-17-norkauran-18-carbonate Ester was written by Cai, Jin;Zhou, Wen;Chen, Junqing;Sun, Min;Ji, Min. And the article was included in Journal of Chemical Crystallography in 2009.Application In Synthesis of Chloromethyl benzoate This article mentions the following:
Isosteviol derivative: benzoyloxymethyl (4α,8β,13β)-13-methyl-16-oxo-17-norkauran-18-carbonate ester was synthesized by esterification of isosteviol with chloromethyl benzoate and its crystal structure was determined by x-ray diffraction method. The compound crystallizes in the triclinic space group P1 with a = 8.784(3) Å, b = 9.079(3) Å, c = 15.950(6) Å, α = 79.343(6)°, β = 79.061(5)°, γ = 89.849(5)°, Z = 2. The conformation of rings A and B is chair, whereas the conformation of ring C is unsym. twist chair. The carbonyl group at the C20 is coplanar with the benzene ring. The fragment of the ester group occupying the pseudoaxial site of C1 position adopts a zigzag conformation. In the experiment, the researchers used many compounds, for example, Chloromethyl benzoate (cas: 5335-05-7Application In Synthesis of Chloromethyl benzoate).
Chloromethyl benzoate (cas: 5335-05-7) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Application In Synthesis of Chloromethyl benzoate
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics