2-Pyridyl and 3-pyridylzinc bromides: direct preparation and coupling reaction was written by Kim, Seung-Hoi;Rieke, Reuben D.. And the article was included in Tetrahedron in 2010.Synthetic Route of C8H4ClNO This article mentions the following:
A facile synthetic approach to the direct preparation of 2-pyridyl and 3-pyridylzinc bromides I (X = CH2, N; Y = N, CH2) has been demonstrated using Rieke zinc with 2-bromopyridine and 3-bromopyridine, resp. A variety of different electrophiles have been coupled with the resulting organozinc reagents to give the corresponding cross-coupling products in moderate to good yields. In the experiment, the researchers used many compounds, for example, 3-Cyanobenzoyl chloride (cas: 1711-11-1Synthetic Route of C8H4ClNO).
3-Cyanobenzoyl chloride (cas: 1711-11-1) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Synthetic Route of C8H4ClNO
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics