Goldstein, Henri et al. published their research in Helvetica Chimica Acta in 1944 | CAS: 5344-49-0

2-Chloro-6-nitrobenzoic acid (cas: 5344-49-0) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Category: chlorides-buliding-blocks

Nitro and nitroamino derivatives of o-chlorobenzoic acid was written by Goldstein, Henri;Preitner, Gaston. And the article was included in Helvetica Chimica Acta in 1944.Category: chlorides-buliding-blocks This article mentions the following:

It has been shown that nitration of 2,5-Cl(AcNH)C6H3CO2H gives 2,5,6-Cl(AcNH) (O2N)C6H2CO2H (I) (C. A. 32, 2521.2). I (1.08 g.) in 10 cc. absolute alc. and 0.6 cc. concentrated H2SO4 at -10° was treated with 1.1 g. of iso-AmNO2 at 0° for 1 h. The reaction product was refluxed for 1 h. in the presence of a trace of Zn and worked up, yielding 0.32 g. (30%) of 2,6-Cl(O2N)C6H3CO2H, m. 163°, identical with the compound obtained by Lehmstedt and Schrader by the oxidation of 2,6-Cl(O2N)C6H3Me (C. A. 31, 4670.7), transformed by refluxing with SOCl2 to 6-nitro-2-chlorobenzoyl chloride, m. 32-4°, b12-13 160°; Me ester, m. 94-5°; Et ester, m. 49-50°; amide, C7H5ClN2O3, m. 186-7°; anilide, m. 176-7°. The nitration of 2,5-Cl(AcNH)C6H3Me (prepared by the chlorination of 18 g. m-MeC6H4NHAc) in a mixture of 18 cc. HNO3 (d. 1.40) and 18 cc. HNO3 (d. 1.52) below 15° for 2 h. yielded 4.0-4.5 g. of 4-nitro-5-acetamido-2-chlorotoluene (II), m. 113°, and a small amount of the isomeric 6-nitro-5-acetamido-2-chlorotoluene (IIa), m. 152-3° (from alc.). Oxidation of 1.15 g. II in 100 cc. H2O containing 2 g. MgSO4 at 100° by addition of 3 g. KMnO4 in 60 cc. H2O for 3 h. and recrystallization of the product from AcOH produced 0.5 g. of 4-nitro-5-acetamido-2-chlorobenzoic acid, m. 214°, saponified to the corresponding 4-nitro-5-amino-2-chlorobenzoic acid, m. 239-40° (decomposition). A similar oxidation of IIa gave I, saponified to the corresponding 2,5,6-Cl(H2N) (O2N)C6H2CO2H. In the experiment, the researchers used many compounds, for example, 2-Chloro-6-nitrobenzoic acid (cas: 5344-49-0Category: chlorides-buliding-blocks).

2-Chloro-6-nitrobenzoic acid (cas: 5344-49-0) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics