Direct oxidative coupling of amidine hydrochlorides and methylarenes: TBHP-mediated synthesis of substituted 1,3,5-triazines under metal-free conditions was written by Guo, Wei. And the article was included in Organic & Biomolecular Chemistry in 2015.Name: 2-Chloro-benzamidine hydrochloride This article mentions the following:
Various 2,4,6-trisubstituted 1,3,5-triazines I (R = C6H5, 4-ClC6H4, cyclopropyl, etc.; Ar = 5-Br-2-H3COC6H3, 1-naphthyl, thiophen-2-yl, etc.) were smoothly formed via TBHP-mediated direct oxidative coupling of amidine and methylarenes. This tandem oxidation-imination-cyclization transformation exhibits a straightforward protocol to prepare 1,3,5-triazines I from easily available starting materials and green oxidants under metal-free conditions. In the experiment, the researchers used many compounds, for example, 2-Chloro-benzamidine hydrochloride (cas: 18637-02-0Name: 2-Chloro-benzamidine hydrochloride).
2-Chloro-benzamidine hydrochloride (cas: 18637-02-0) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Name: 2-Chloro-benzamidine hydrochloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics