Convenient Access to C10- and C11-(di)arylated dibenzo[b,f]azepines via Palladium-catalyzed C-H Bonds Cleavages was written by Li, Haoran;Roisnel, Thierry;Soule, Jean-Francois;Doucet, Henri. And the article was included in Advanced Synthesis & Catalysis in 2019.Related Products of 777-44-6 This article mentions the following:
Conditions allowing the C10- and C11-arylations of dibenzo[b,f]azepines via successive palladium-catalyzed reactions are reported. Using aryl bromides as the aryl source, the C10-arylation of dibenzo[b,f]azepines is very selective. Then, using benzenesulfonyl chlorides as the aryl source, the second arylation at C11-position is achieved affording non-sym. C10,C11-diarylated dibenzo[b,f]azepines I (R = n-Pr, i-Pr, Bn, Ph; Ar1 = Ph, 4-MeC6H4, 3-OMeC6H4, 2-MeC6H4, 3-Py, 2-Naph, etc; Ar2 = Ph, 4-tBuC6H4, 3-CF3C6H4, 2-MeC6H4, etc). Both reactions tolerate a variety of substituents on the aryl source. In the experiment, the researchers used many compounds, for example, 3-(Trifluoromethyl)benzene-1-sulfonyl chloride (cas: 777-44-6Related Products of 777-44-6).
3-(Trifluoromethyl)benzene-1-sulfonyl chloride (cas: 777-44-6) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Related Products of 777-44-6
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics