Bioengineering of CuO porous (nano)particles: role of surface amination in biological, antibacterial, and photocatalytic activity was written by Bagherzadeh, Mojtaba;Safarkhani, Moein;Ghadiri, Amir Mohammad;Kiani, Mahsa;Fatahi, Yousef;Taghavimandi, Fahimeh;Daneshgar, Hossein;Abbariki, Nikzad;Makvandi, Pooyan;Varma, Rajender S.;Rabiee, Navid. And the article was included in Scientific Reports in 2022.Formula: C16H18ClN3S This article mentions the following:
Nanotechnol. is one of the most impressive sciences in the twenty-first century. Not surprisingly, nanoparticles/nanomaterials have been widely deployed given their multifunctional attributes and ease of preparation via environmentally friendly, cost-effective, and simple methods. Although there are assorted optimized preparative methods for synthesizing the nanoparticles, the main challenge is to find a comprehensive method that has multifaceted properties. The goal of this study has been to synthesize aminated (nano)particles via the Rosmarinus officinalis leaf extract-mediated copper oxide; this modification leads to the preparation of (nano)particles with promising biol. and photocatalytic applications. The synthesized NPs have been fully characterized, and biol. activity was evaluated in antibacterial assessment against Bacillus cereus as a model Gram-pos. and Pseudomonas aeruginosa as a model Gram-neg. bacterium. The bio-synthesized copper oxide (nano)particles were screened by MTT assay by applying the HEK-293 cell line. The aminated (nano)particles have shown lower cytotoxicity (鈭?21%), higher (鈭?50%) antibacterial activity, and a considerable increase in 味 potential value (鈭?+ 13.4 mV). The prepared (nano)particles also revealed considerable photocatalytic activity compared to other studies wherein the dye degradation process attained 97.4% promising efficiency in only 80 min and just 7% degradation after 80 min under dark conditions. The biosynthesized copper oxide (CuO) (nano)particle’s biomedical investigation underscores an eco-friendly synthesis of (nano)particles, their noticeable stability in the green reaction media, and impressive biol. activity. In the experiment, the researchers used many compounds, for example, 3,7-Bis(dimethylamino)phenothiazin-5-ium chloride (cas: 61-73-4Formula: C16H18ClN3S).
3,7-Bis(dimethylamino)phenothiazin-5-ium chloride (cas: 61-73-4) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Formula: C16H18ClN3S
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics