Reactivity of benzylic acylammonium chlorides. A novel method for the synthesis of N-phenacylamides was written by Coskun, Necdet;Tirli, Fatma. And the article was included in Synthetic Communications in 1997.Name: 2-(3-Methoxyphenyl)acetyl chloride This article mentions the following:
Tertiary amines R1C6H4CH2NR2CH2COC6H4R3-4 [R1 = H, 2,3-(MeO)2, 3,4-(MeO)2, 2-NO2, etc., R2 = Me, PhCH2, 3,4-(MeO)2C6H3CH2, R3 = H, MeO] reacted with acid chlorides R4COCl [R4 = 3-MeOC6H4CH2, 3,4-(MeO)2C6H4CH2, PhCH2, 4-MeOC6H4CH2] to give corresponding benzyl chlorides and N-phenacylamides R4CONR2CH2COC6H4R3-4. The effect of the substituents in the benzyl group on the reactivity of the intermediate acylammonium chlorides was investigated. In the experiment, the researchers used many compounds, for example, 2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0Name: 2-(3-Methoxyphenyl)acetyl chloride).
2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Name: 2-(3-Methoxyphenyl)acetyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics