Iodide-Catalyzed Carbonylation-Benzylation of Benzyl Chlorides with Potassium Aryltrifluoroborates under Ambient Pressure of Carbon Monoxide was written by Han, Wei;Chen, Junjie;Jin, Fengli;Yuan, Xiaorong. And the article was included in Synlett in 2018.Electric Literature of C8H9Cl This article mentions the following:
The novel transition-metal free synthesis of a wide range of 1,2,3-triarylpropan-1-ones R1CH2CHR1C(O)R2 (R1 = Ph, 3,4-Cl2C6H3, 3-MeOC6H4, etc.; R2 = Ph, 4-FC6H4, 2-naphthyl, etc.) in high yields was developed via tetrabutylammonium iodide-catalyzed carbonylation-benzylation of unactivated benzyl chlorides R1CH2Cl with potassium aryltrifluoroborates R2BF3K using CO gas under ambient pressure. This protocol provides an inexpensive and operationally simple method for synthesis of 1,2,3-triarylpropan-1-ones and represented a significant improvement over the traditional palladium-catalyzed carbonylation. In the experiment, the researchers used many compounds, for example, 1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9Electric Literature of C8H9Cl).
1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Electric Literature of C8H9Cl
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics