Solid-phase synthesis of 2,3-diphenylpropionic acid library as VLA-4 antagonists was written by Hoshina, Yoichiro;Ikegami, Satoru;Fujimoto, Kyoko;Okuyama, Akihiko;Harada, Tatsuhiro;James, Susan;Griffiths, Peter G.;Wu, Zemin;Lilly, Michael;Bray, Andrew M.. And the article was included in Tetrahedron Letters in 2005.Recommanded Product: 3-Cyanobenzoyl chloride This article mentions the following:
A 2,3-diphenylpropionic acid library was synthesized on solid-phase. There are two practical synthetic routes via an orthogonal generation of two aromatic amino functional groups. Several compounds were identified as potent VLA-4 antagonists. In the experiment, the researchers used many compounds, for example, 3-Cyanobenzoyl chloride (cas: 1711-11-1Recommanded Product: 3-Cyanobenzoyl chloride).
3-Cyanobenzoyl chloride (cas: 1711-11-1) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Recommanded Product: 3-Cyanobenzoyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics